For this paper, ca. 55 km high-resolution reflection seismic data were interpreted using constraints from magnetotelluric, potential field, and geological data. The resulting integrated geological-geophysical section through the central Caledonides in Sweden provides new insights about the regional tectonic setting, and supplies the basis for siting the second drill hole of the Collisional Orogeny in the Scandinavian Caledonides (COSC) scientific drilling project.